A critical analysis of the long term impact of radical prostatectomy on cancer control and functional outcomes

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In an article by Boorjian et al (Eur Urol 61 (2012) 664-675) the literature published between 1980 and 2011 was reviewed. Less than 10% of all men treated by radical prostatectomy died from prostate cancer within 15 years of surgery. The authors comment that radical prostatectomy has been associated with a 40% decrease in risk of death from prostate cancer compared to watchful waiting quoting Bill-Axelson et al in NEJM (2011). They also comment on slack of evidence directly comparing the results of surgery versus radiotherapy, although they quote Abdollah et al in Eur Urol (2011), who reported on 404,604 patients treated for low and intermediate risk prostate cancer recorded by the SEER database, with surgery having the lowest risk of cancer and all cause mortality (3.6% at 10 years compared to 6.5% for radiotherapy).

97 Responses to A critical analysis of the long term impact of radical prostatectomy on cancer control and functional outcomes

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