In an article by Nyarangi-Dix et al published in J Urol (2012), the authors show that continence is better in patients treated by bladder neck preservation during radical prostatectomy than those without bladder neck preservation. They conducted a randomised study involving 208 men treated with radical prostatectomy at their institution. The patients did not know if they had the complete bladder neck preservation (cBNP) procedure or not. All the patients completed 12 months of follow-up. After excluding nine subjects, the analysis included 95 men who were assigned to cBNP and 104 non-BNP controls.
Surgical margin positivity rates were not significantly different between the two groups at 14.7% and 12.5%. Rates of social continence – defined as use of no more than one pad per day – were 84.2% vs 55.3% (p<0.001) at three months and 94.7% vs 81.4% (p=0.027) at 12 months, favouring cBNP. This study confirms many previous reports from retrospective data, and is similar to results from patients treated at the Staffordshire Urology Clinic.