In an article published in Human Reproduction (2012), the authors show that sperm concentration in semen of French men fell by 32% over a 17 year period. 26 609 partners of totally infertile women undergoing an assisted reproductive technology (ART) procedures in the whole of France were studied between 1989 and 2005. There was a continuous decline in concentration during this time.
This study adds to the debate about a global decrease in human sperm quality. Many small and sometimes methodologically flawed studies have reported similar temporal trends. There is growing biological, toxicological, experimental and human exposure data to support the endocrine disruptors’ hypothesis assuming that foetal exposure to endocrine disruptors could impair reproductive outcomes.
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